Review papers
Deciphering the acetylation code of p53 in transcription regulation and tumor suppression
Z Xia, N Kon, AP Gu, O Tavana, W Gu
Oncogene. 2022.
doi: 10.1038/s41388-022-02331-9. PMID: 35487975
p53 in ferroptosis regulation: the new weapon for the old guardian
Liu Y, Gu W.
Cell Death Differ. 2022.
doi: 10.1038/s41418-022-00943-y. PMID: 35087226
The complexity of p53-mediated metabolic regulation in tumor suppression.
Liu Y, Gu W.
Semin Cancer Biol. 2021.
doi: 10.1016/j.semcancer.2021.03.010. PMID: 33785447
Emerging Mechanisms and Disease Relevance of Ferroptosis.
Stockwell BR, Jiang X, Gu W.
Trends Cell Biol. 2020.
doi: 10.1016/j.tcb.2020.02.009. PMID: 32413317
Deubiquitinases: Pro-oncogenic Activity and Therapeutic Targeting in Blood Malignancies.
Gutierrez-Diaz BT, Gu W, Ntziachristos P.
Trends Immunol. 2020.
doi: 10.1016/j.it.2020.02.004. PMID: 32139316
Mutant p53 on the Path to Metastasis.
Tang Q, Su Z, Gu W, Rustgi AK.
Trends Cancer. 2020.
doi: 10.1016/j.trecan.2019.11.004. PMID: 31952783
p53 modifications: exquisite decorations of the powerful guardian.
Liu Y, Tavana O, Gu W.
J Mol Cell Biol. 2019.
doi: 10.1093/jmcb/mjz060. PMID: 31282934
Targeting HAUSP in both p53 wildtype and p53-mutant tumors.
Tavana O, Sun H, Gu W.
Cell Cycle. 2018.
doi: 10.1080/15384101.2018.1456293. PMID: 29616860
To be, or not to be: functional dilemma of p53 metabolic regulation.
Wang SJ, Gu W.
Curr Opin Oncol. 2014.
doi: 10.1097/CCO.0000000000000024. PMID: 24240177
Dual Roles of MDM2 in the Regulation of p53: Ubiquitination Dependent and Ubiquitination Independent Mechanisms of MDM2 Repression of p53 Activity.
Shi D, Gu W.
Genes Cancer. 2012.
doi: 10.1177/1947601912455199. PMID: 23150757
p53 post-translational modification: deregulated in tumorigenesis.
Dai C, Gu W.
Trends Mol Med. 2010.
doi: 10.1016/j.molmed.2010.09.002. PMID: 20932800
Modes of p53 regulation.
Kruse JP, Gu W.
Cell. 2009.
doi: 10.1016/j.cell.2009.04.050. PMID: 19450511
How does SIRT1 affect metabolism, senescence and cancer?
Brooks CL, Gu W.
Nat Rev Cancer. 2009.
doi: 10.1038/nrc2562. PMID: 19132007
Dissecting roles of ubiquitination in the p53 pathway.
Shan J, Brooks C, Kon N, Li M, Gu W.
Ernst Schering Found Symp Proc. 2008.
doi: 10.1007/2789_2008_105. PMID: 19202598
p53 ubiquitination: Mdm2 and beyond.
Brooks CL, Gu W.
Mol Cell. 2006.
doi: 10.1016/j.molcel.2006.01.020. PMID: 16455486
Dynamics in the p53-Mdm2 ubiquitination pathway.
Brooks CL, Gu W.
Cell Cycle. 2004.
doi: 10.4161/cc.3.7.997. PMID: 15254415
Dynamics of the p53 acetylation pathway.
Gu W, Luo J, Brooks CL, Nikolaev AY, Li M.
Novartis Found Symp. 2004.
PMID: 15171255
Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation.
Brooks CL, Gu W.
Curr Opin Cell Biol. 2003.
doi: 10.1016/s0955-0674(03)00003-6. PMID: 12648672