Review papers

  1. Deciphering the acetylation code of p53 in transcription regulation and tumor suppression

    Z Xia, N Kon, AP Gu, O Tavana, W Gu

    Oncogene. 2022.

     doi: 10.1038/s41388-022-02331-9. PMID: 35487975

  2. p53 in ferroptosis regulation: the new weapon for the old guardian

    Liu Y, Gu W.

    Cell Death Differ. 2022.

    doi: 10.1038/s41418-022-00943-y. PMID: 35087226

  3. The complexity of p53-mediated metabolic regulation in tumor suppression.

    Liu Y, Gu W.

    Semin Cancer Biol. 2021.

    doi: 10.1016/j.semcancer.2021.03.010. PMID: 33785447

  4. Emerging Mechanisms and Disease Relevance of Ferroptosis.

    Stockwell BR, Jiang X, Gu W.

    Trends Cell Biol. 2020.

    doi: 10.1016/j.tcb.2020.02.009. PMID: 32413317

  5. Deubiquitinases: Pro-oncogenic Activity and Therapeutic Targeting in Blood Malignancies.

    Gutierrez-Diaz BT, Gu W, Ntziachristos P.

    Trends Immunol. 2020.

    doi: 10.1016/j.it.2020.02.004. PMID: 32139316

  6. Mutant p53 on the Path to Metastasis.

    Tang Q, Su Z, Gu W, Rustgi AK.

    Trends Cancer. 2020.

    doi: 10.1016/j.trecan.2019.11.004. PMID: 31952783

  7. p53 modifications: exquisite decorations of the powerful guardian.

    Liu Y, Tavana O, Gu W.

    J Mol Cell Biol. 2019.

    doi: 10.1093/jmcb/mjz060. PMID: 31282934

  8. Targeting HAUSP in both p53 wildtype and p53-mutant tumors.

    Tavana O, Sun H, Gu W.

    Cell Cycle. 2018.

    doi: 10.1080/15384101.2018.1456293. PMID: 29616860

  9. To be, or not to be: functional dilemma of p53 metabolic regulation.

    Wang SJ, Gu W.

    Curr Opin Oncol. 2014.

    doi: 10.1097/CCO.0000000000000024. PMID: 24240177

  10. Dual Roles of MDM2 in the Regulation of p53: Ubiquitination Dependent and Ubiquitination Independent Mechanisms of MDM2 Repression of p53 Activity.

    Shi D, Gu W.

    Genes Cancer. 2012.

    doi: 10.1177/1947601912455199. PMID: 23150757

  11. p53 post-translational modification: deregulated in tumorigenesis.

    Dai C, Gu W.

    Trends Mol Med. 2010.

    doi: 10.1016/j.molmed.2010.09.002. PMID: 20932800

  12. Modes of p53 regulation.

    Kruse JP, Gu W.

    Cell. 2009.

    doi: 10.1016/j.cell.2009.04.050. PMID: 19450511

  13. How does SIRT1 affect metabolism, senescence and cancer?

    Brooks CL, Gu W.

    Nat Rev Cancer. 2009.

    doi: 10.1038/nrc2562. PMID: 19132007

  14. Dissecting roles of ubiquitination in the p53 pathway.

    Shan J, Brooks C, Kon N, Li M, Gu W.

    Ernst Schering Found Symp Proc. 2008.

    doi: 10.1007/2789_2008_105. PMID: 19202598

  15. p53 ubiquitination: Mdm2 and beyond.

    Brooks CL, Gu W.

    Mol Cell. 2006.

    doi: 10.1016/j.molcel.2006.01.020. PMID: 16455486

  16. Dynamics in the p53-Mdm2 ubiquitination pathway.

    Brooks CL, Gu W.

    Cell Cycle. 2004.

    doi: 10.4161/cc.3.7.997. PMID: 15254415

  17. Dynamics of the p53 acetylation pathway.

    Gu W, Luo J, Brooks CL, Nikolaev AY, Li M.

    Novartis Found Symp. 2004.

    PMID: 15171255

  18. Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation.

    Brooks CL, Gu W.

    Curr Opin Cell Biol. 2003.

    doi: 10.1016/s0955-0674(03)00003-6. PMID: 12648672